1.
Ann Pharm Fr
; 53(1): 29-37, 1995.
Artigo
em Francês
| MEDLINE
| ID: mdl-7741424
RESUMO
Primary amines react with two formaldehydes and compounds presenting two mobile hydrogen atoms, this reaction can be called iminodimethylation. This reaction can be used in order to perform a pharmacomodulation in the pyrimido [3,4-a]-s-triazine series. Against Epidermophyton floccosum, the activity is better when nitrogen 7 is not substituted, when the heroatom in position 2 is 0 instead of S and when an aromatic nucleus is directly linked to the nitrogen atom in position 3.
Assuntos
Antifúngicos/síntese química , Bactérias/efeitos dos fármacos , Pirimidinas/farmacologia , Triazinas/farmacologia
2.
Ann Pharm Fr
; 42(3): 271-82, 1984.
Artigo
em Francês
| MEDLINE
| ID: mdl-6508155